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Friday, April 24, 2020

We Can’t Go on Like This Much Longer - New York Magazine

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I began to lose it this week.

I know, I have it very easy. I’m not required to put myself at risk every day as a hospital or essential worker. I’m still employed. I’ve got some savings, and don’t have to worry about basic survival. I get food delivered. I haven’t lost any family members or friends from COVID-19 (though I did lose my dad in a horrible accident, and couldn’t get to the burial). My apartment gets plenty of sun and I have two dogs who love me. I get a couple of good walks in a day, and have plenty to read. I don’t have kids. I have direct, personal experience of living through a plague once before in my life.

All of that should make me a prime candidate to hang in, take this period as a disciplinary exercise, and generally be a good citizen. And I have been — I haven’t had any physical human contact for two months now, I wear a mask everywhere, I use rubber disposable gloves for groceries, I keep my six-feet distance so far as I can, even though it’s impossible in my neighborhood to walk on a sidewalk or in a park and not be accosted by joggers, who routinely come within inches of my face. I have no intention of breaking any of these rules, although I am tempted by homicide if any of these fit, entitled motherfuckers actually spit on the ground near me.

But I can recognize signs of psychological and physical stress, and I’m beginning to lose it. This week, for some reason, Wednesday was a bad day. Or at least I think it was Wednesday. What day is it again?

My sleep patterns are totally screwed up, and I find myself waking up tense several times a night, or crashing out for 10 or 12 hours at a time. I wake up and want to go back to sleep. My appetite is waning, and my body longs for some weights to push and pull. My teeth grind all night long and my jaw is tense. I have all the time in the world to read and write, and yet I find myself anesthetized with ennui, procrastinating and distracting myself. Yes, I scan the news every day, often hourly, to discern any seeds of progress.

And here’s the thing: I can’t see much on the horizon.

Yes, it’s a big relief that our hospitals are no longer overwhelmed and daily deaths have plateaued or even declined a little. Yes, the epidemiological worst has not happened — largely because of the new behavioral rules — even though we could well be headed past the White House’s estimate of 60,000 casualties in the medium term, and countless more whose bodies will be permanently wracked by the damage this virus does to the lungs and heart and kidneys.

But I’m also aware that even this modest arrest of a previously exponential disease has only delayed the inevitable. “Flattening the curve” has actually been a remarkable success — but its very success will likely draw this epidemic out for months and years. Yes, if you’re being super-realistic: years. Vaccines do not happen overnight — and even an 18-month deadline for vaccine salvation is being optimistic. We still don’t have a vaccine for HIV, and probably never will. HIV is a retrovirus, which is far harder to vaccinate against than a coronavirus, but COVID-19 is exponentially more contagious than HIV, if not as fatal. Remove constraints and it will spread like ink on a napkin.

A yet-to-be-peer reviewed study from China suggests that the virus has so far about 30 mutations, some far more severe than others. It is also unclear that antibodies can even succeed in preventing the disease, and for how long: “Preliminary studies on monkeys suggest COVID-19 antibodies provide partial, short-term protective immunity to reinfection, but, as Harvard epidemiologist Marc Lipsitch recently wrote for the New York Times, these early results are just “educated guesses.” Notice the word: “short-term.” We are going to be dealing with some form of this virus for the indefinite future, and it has a good chance of becoming endemic: “Other coronaviruses, which cause common cold symptoms, lead to a very weak immune response and people can catch the same bug multiple times in their lifetime.” A preliminary study of convalescent patients in China was not encouraging: It found that 30 percent of those who had been infected by COVID-19 had so few antibodies to the disease it was unlikely they’d have any immunity. If this finding turns out to be true (and the study has not yet been peer-reviewed), we’re truly, royally fucked.

Treatments? That’s at least worth some limited optimism. It was treatments — not a vaccine — that allowed us to turn the corner on HIV. And that’s why I still do get up in the morning. The trouble is that it took years to develop effective treatments for the vast array of opportunistic infections, and more than a decade for scientists to come up with an effective treatment for the virus itself.  When a virus is brand new, and we don’t know much about it, it simply takes time to figure out its weak spots, and develop treatments to exploit them. We’re talking several months at best, and — as with HIV treatments — we will be disappointed most of the time. Hydroxycholoroquine turns out, in some patients, to make things worse, not better. Gilead’s remdesivir is one reason I have some hope. Seven clinical trials are underway, and anecdotal studies in Chicago have raised hopes. Yesterday, leaked data from one trial suggests it might be a flop, but that particular trial may also be misleading. We don’t know.

This pattern of hopeful rumors that were later dashed is a familiar one for HIV survivors. There were countless possible treatments for various aspects of AIDS opportunistic infections in the late 1980s and ’90s, and trials were constant. Many succeeded in arresting some aspects of the disease — but many very promising trials turned out to be duds. What looked like breakthroughs in phase three trials often became crushed hopes in phase four. Remdesivir is an already existing drug, designed for Ebola (and eventually rejected in favor of better treatments). AZT was also a preexisting medicine that seemed promising at first, and then we discovered, through rigorous trials, that mono AZT therapy was basically useless, and usually toxic. It took years for researchers to come up with drugs that could, sometimes in combination with AZT, bring viral loads to zero. It may take just as long to develop brand-new treatments that could make a decisive difference with COVID-19.

The obvious massive difference between the race to find treatments for HIV and those for COVID-19 is also that HIV in America was relatively contained within the world of anal sex and intravenous drug use (and still is). The broader society could go on as normal, even though the gay world was experiencing medieval levels of death. With COVID-19, in stark contrast, we have shut down almost our entire economy and restricted all human interaction in unprecedented ways. Even in 1918, there was no national shutdown similar to the one we’ve imposed more than a century later. Yes, there were masks and social distancing and business restrictions, but the most draconian measure, in Saint Louis, shut down all economic activity in only one city for just 48 hours.

So we have created a scenario which has mercifully slowed the virus’s spread, but, as we are now discovering, at the cost of a potentially greater depression than in the 1930s, with no assurance of any progress yet visible. If we keep this up for six months, we could well keep the deaths relatively low and stable, but the economy would all but disintegrate. Just because Trump has argued that the cure could be worse than the disease doesn’t mean it isn’t potentially true. The previously unimaginable levels of unemployment and the massive debt-fueled outlays to lessen the blow simply cannot continue indefinitely. We have already, in just two months, wiped out all the job gains since the Great Recession. In six months? The wreckage boggles the mind.

All of this is why, one some days, I can barely get out of bed. It is why protests against our total shutdown, while puny now, will doubtless grow. The psychological damage — not counting the physical toll — caused by this deeply unnatural way of life is going to intensify. We remain human beings, a quintessentially social mammal, and we orient ourselves in time, looking forward to the future. When that future has been suspended, humans come undone. Damon Linker put it beautifully this week: “A life without forward momentum is to a considerable extent a life without purpose — or at least the kind of purpose that lifts our spirits and enlivens our steps as we traverse time. Without the momentum and purpose, we flounder. A present without a future is a life that feels less worth living, because it’s a life haunted by a shadow of futility.” Or, in the words of the brilliant Freddie deBoer: “The human cost of the disease and those it will kill is enormous. The cost of our prevention efforts are high as well. You’re losing something. You’re losing so much. So you should mourn. We’ve lost the world. Mourn for it.”

We have done what we had to do, and I am not criticizing the shutdown strategy so far. I’m simply saying that it cannot last. We keep postponing herd immunity, if such a thing is even possible with this virus. A massive testing, tracing, and quarantining regime seems beyond the capacity of our federal government in the foreseeable future. And we are a country without a functioning president — ours thinks we should inject bleach to kill COVID-19, and is also doing what he can to divide the nation to keep his fast-diminishing candidacy from imploding. And we know this much after three and a half years: The worse this gets, the worse he will get. Already he is lambasting shutdown orders as well as Georgia’s attempt to end the shutdown. He is an incoherent, malevolent mess of a human being. I used to be disgusted by him. I am now incandescent with rage at him and the cult that enables his abuse of all of us.

And so we wait. Absent a pharmaceutical miracle, we are headed, if we keep this up, toward both a collapse in the economy and an inevitable second wave that will further cull the population. Yes, I’m a catastrophist by nature. I hope and pray something intervenes to save us from this uniquely grim future. But I learned something from the AIDS years: Sometimes it is a catastrophe. And sometimes the only way past something is through it.

Not Her Year

I’m pretty open-minded about who will be Biden’s vice-presidential pick. For reasons of identity politics, he has excluded anyone male in advance, regardless of their abilities — showing how captive Biden is (despite his reputation) to wokeness. But some left identitarians are pushing him to go even woker and exclude white women from consideration too. (A majority of white women voted for Trump last time around, after all!)

Whatever you make of that argument, it is quite true that black women are critical to the Democratic Party base. In that context, Stacey Abrams’s name keeps coming up. So let me state for the record that as a pure political calculation, I think she’d be a bad candidate for the job.

Abrams is hobbled for reasons that have nothing to do with her race or gender. She has no national experience, and her only political record is in being a state legislator and House minority leader in Georgia’s House of Representatives, and a failed gubernatorial candidate. As a legislator, she never faced a Republican candidate, running unopposed in all her elections for the 89th District.

The only competitive election she ran in, for governor, she lost, with a massive black and white turnout. Even the young and untested Barack Obama had won a Senate race in a landslide, with 70 percent of the vote in a seat previously occupied by a Republican, before he ran for president. That option would have been open to Abrams in Georgia after her defeat in 2018, and she could have proved her strength and elevated her profile in the Senate. Democrats  awarded her the response to Trump’s State of the Union address — the first ever for someone holding no elected position. And she was recruited hard to run for the Senate — but, after toying with the idea, she decided against. According to her, she is focused on becoming president and this will happen within the next 20 years.

The main problem is that she continues to claim that her loss in her only competitive election was a function of a rigged electoral process. This is a stance that could legitimize any complaints Trump might have if he loses narrowly in November. Abrams doesn’t just claim that voter suppression was real (it was) and that she was therefore running with one hand tied behind her back (like most Democrats in the South, she was). She goes further: “I cannot say that everybody who tried to cast a ballot would’ve voted for me, but if you look at the totality of the information, it is sufficient to demonstrate that so many people were disenfranchised and disengaged by the very act of the person who won the election that I feel comfortable now saying, ‘I won.’”

She strongly implies that no one responsible for the voter rolls — as Kemp was in his role as Georgia’s secretary of State, and who can thereby theoretically rig them — should be able to run. But by that logic, all governors could be barred from running for reelection. She could have conceded the race and then drawn attention to voter suppression, which is indeed a vital issue. But she didn’t. She still won’t concede. If Trump does the same later this year, after a close (or even not-so-close) defeat, he’ll be able to use it against her and thereby Biden. He’s already teeing up the argument. In his presser yesterday, asked whether an election result while a pandemic is still raging in some parts of the country could be challenged, Trump responded: “Good question!” I’ve long feared that Trump will not be able to concede a close election, because he is psychologically incapable of conceding anything. We may well face a constitutional crisis in November. Stacey Abrams must not be Trump’s trump card, allowing him to muddy the waters.

The other problem is her open identity politics. Hovering just beneath the surface in her current media campaign for herself is a form of leverage: She is all but claiming outright that being a black woman is indeed a central credential within the Democratic Party, and that a white female candidate could thereby divide the party and fail to attract the high black turnout the Dems need to win. On The View this week she said: “I share your concern about not picking a woman of color because women of color, particularly because black women are the strongest part of the Democratic Party.”

No argument on the latter, but are black women overall demanding a black female candidate? Not really. In the primaries, black voters overwhelmingly voted for a white man, Joe Biden, and showed no real enthusiasm for any of the black candidates. And the data do not suggest that black voters will only show up for a black candidate. In fact, polling says they are much less concerned than white liberals with the race and gender of their nominee.

If you want a minority woman, think Senator Kamala Harris, who has national experience, the courage to run for the highest office, and a record of actually winning competitive elections. If you want a white woman, there are also plenty to choose from. But Abrams? She herself has said it is inevitable she will be president within the next 20 years. So why not wait?

The Government’s Failure Is Much Bigger Than Trump

In the middle of this pandemic, I can’t get out of my mind that the budget for the Centers for Disease Control and Prevention last year was $7.2 billion. This year, it will set a record of $7.9 billion — an all-time record. That’s an incredible sum. The FDA, the other critical agency for controlling disease, has a comparable $5.7 billion budget. The WHO is funded by the U.S. to the tune of $453 million, by far the biggest contributor.

The federal agencies tasked with preparing for a pandemic response are also numerous and absorb a huge amount of federal dollars. Judge Glock, a policy analyst at the Cicero Institute, explains: “The acronyms of those agencies that are supposed to organize a response to a communicable disease crisis include, but are not limited to, the ASPR, CDC, DGMQ, NCEZID, USSG, HHS, FEMA, FDA, NIAID, DOD, DHS, NSC, CTF, and associated sub-agencies and divisions and offices.”

And one might imagine that all of this kind of spending would help us, you know, control disease. But nah. COVID-19 took a brief glance at these hugely expensive bodies and carried on its culling of the population unmolested. In the most critical disease outbreak in a century, all these well-funded groups turned out to be incapable of making any kind of difference when it mattered. Their lines of command are confusing, and their legislative mandates overlap. Plans for preparedness are so manifold, no one knows quite which one to pick. The result is that we were ready for an epidemic like the one we’re enduring. In fact, we were perhaps overly prepared. The trouble has been incompetence.

Yes, it did not help that the Trump administration significantly cut the CDC presence in China in the last two years, but it should have been perfectly possible for the staff that remained to stay on top of the most infectious and deadly pandemic disease in a century. In December 2019, after all, the heroic whistle-blower, Li Wenliang, had broken the news of a new SARS-like coronavirus spreading in Wuhan. You could find the rumors on the fucking internet.

But the CDC and the WHO trusted the Chinese government to help them — and the communist dictatorship was determined at first to hush the outbreak up: “Health and Human Services secretary, Alex Azar, did make the effort to get U.S. experts inside. The department reached out to China in the first week of January, and secretary Azar asked his Chinese counterpart again in late January. China resisted outsiders, both from the U.S. and WHO.” But it is also true — and this is critical — that the WHO head, Tedros Adhanom Ghebreyesus, was in direct communication with the Chinese dictatorship, and was naïve to trust them; and on January 10, the Chinese published the genetic sequence for the disease. Maybe we lost a couple of weeks, but after that, we no longer needed the Chinese, or the WHO. We had the data; we needed a plan of action.

The CDC initiated an attempt to create a test for COVID-19, achieving it in a mere seven days. But somehow they fucked it up, and we still have no good explanation why. Did they rush it? Or were they the most incompetent disease control agency on the planet? The test, first used in New York, turned out to be flawed and effectively useless. More to the point, once a public emergency had been declared, FDA regulations prevented private parties from creating a more effective test. A test emerged from the WHO, but the CDC did not throw everything overboard to adopt it. And, again, we still don’t really know why.

The FDA, for its part, refused to lift the mind-numbing bureaucratic procedures to expedite independent labs from creating a viable test. And so we were flying blind — and we still are. Billions and billions of dollars over decades for multiple agencies and legislation passed last year precisely to prevent such an outbreak — and here we are, with no end in sight, forced to stay inside because the fully funded federal machine could not move fast enough, and when it did, failed a core competency test.

You can assail Trump’s pathetic and incoherent response. I’m not going to quibble. But this was much deeper than merely Trump’s failure. It was and is the failure of the entire federal bureaucracy, which has been exorbitantly funded to prevent exactly such an emergency and spectacularly, unforgivably, failed.

See you next Friday.

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